Chronic Fatigue Explained: Hormones, Micronutrients & Mitochondrial Testing

Chronic fatigue is more than just feeling tired—it’s a persistent lack of energy that doesn’t improve with rest. Many patients are told their blood tests are “normal,” yet symptoms continue. This is where advanced fatigue testing becomes essential, focusing on deeper physiological imbalances. 

Hormonal health plays a central role in energy regulation. Imbalances in thyroid hormones, cortisol, or sex hormones such as testosterone and oestrogen can significantly impact metabolism, mood, and stamina. Even subtle disruptions can lead to ongoing fatigue. 

Micronutrient deficiencies are another overlooked cause. Key nutrients like iron, vitamin B12, magnesium, and vitamin D are critical for cellular energy production. Standard tests may miss borderline or functional deficiencies that still affect performance and wellbeing. 

At the cellular level, mitochondrial function is crucial. Mitochondria are responsible for producing energy (ATP), and dysfunction can result in low energy, brain fog, and poor recovery. Advanced testing can assess markers of oxidative stress and mitochondrial efficiency, offering a clearer picture of underlying issues. 

By combining hormonal, micronutrient, and mitochondrial insights, a more accurate and personalised approach to fatigue can be achieved. For those seeking a fatigue test in London, advanced assessments at Levitas Diagnostics provide a comprehensive evaluation to identify root causes and support long-term energy optimisation. 

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